Recalls (12)
NHTSA lists 12 recall campaigns for the 2021 Mercedes-Benz E350. Check whether yours was repaired with NHTSA's free VIN lookup ↗
Only NHTSA and your automaker know whether your specific car was repaired. PlainVIN shows every recall campaign listed for a model year, with the official text and how many cars have been fixed so far.
Check on NHTSA ↗Loss of Drive Power from Fuel Pump Shutdown
- Summary
- Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 C-Class, E-Class, S-Class, CLS, SL, GT, GLC, GLE, GLS, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, which can result in a loss of drive power.
- Consequence
- A loss of drive power can increase the risk of a crash.
- Remedy
- Dealers will replace the fuel pump, free of charge. Owner notification letters were mailed on June 14, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2023070012.
Disabled Emergency Call System
- Summary
- Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2017-2022 CLA-Class, GLA-Class, GLE-Class, GLS-Class, SLC-Class, A-Class, AMG GT-Class, C-Class, E-Class, S-Class, SL-Class, GLC-Class, CLS-Class, GLB-Class, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle model details. An error in the communication module's SIM card software can cause a mobile network connection failure, disabling the emergency call (eCall) system.
- Consequence
- A disabled eCall system would prevent a vehicle occupant from contacting the emergency services call center in an emergency, potentially delaying emergency responders and increasing the risk of injury.
- Remedy
- The communication module software will be updated through an Over-the-Air (OTA) update or by a dealer, free of charge. Owner notification letters were mailed July 8, 2022. Owner notification letters will be mailed in phases, on July 8, 2022, May 17, 2024, July 29, 2024, and September 27, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's numbers are for this recall is 2022060005 and 2023110006.
Inoperable Rearview Camera Display/FMVSS 111
- Summary
- Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2018-2021 CLA-Class, GLE/GLS-Class, A-Class, C-Class, E-Class, E-Class Coupe/Convertible, GLA/GLB-Class, GLC-Class, and CLS-Class vehicles. Please refer to MBUSA's recall report for specific vehicle model details. The rearview camera may not display the rearview image due to a software error. As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard number 111, "Rear Visibility."
- Consequence
- An inoperable rearview camera display reduces the driver's rear view, increasing the risk of a crash.
- Remedy
- Dealers will update the rearview camera software, free of charge. Owner notification letters were mailed July 15, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022060007.
Steering Wheel Hands-Off Detection Software Error
- Summary
- Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2022 C-Class, E-Class, S-Class, SL, EClass Coupe/Convertible, CLS, AMG GT 4-doors Coupe, and EQS vehicles with a heated leather steering wheel. Due to a software error in the hand detection control unit, the hands-off detection might not detect when the driver's hands are away from the steering wheel when using the Active Distance Assist DISTRONIC system.
- Consequence
- Deactivated hands-off detection will prevent DISTRONIC system features from functioning, including warnings to grab the steering wheel and calling first responders as part of the Active Emergency Stop Assist, which can increase the risk of a crash or injury.
- Remedy
- Dealers will update the hand detection control unit software for the DISTRONIC system, free of charge. Owner notification letters were mailed May 6, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022040010.
Side Impact Crash Sensor Connectors May Loosen
- Summary
- Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 CLS450, AMG E53, AMG CLS53, E350, E450, AMG GT43, AMG GT53, 2020 S450, S560, G550, AMG GLC63, 2020-2021 GLC300, and AMG G63 vehicles. The side crash sensor connectors may come loose, which could delay the activation of air bags and seatbelts during a side impact crash.
- Consequence
- Air bags and seatbelts that don't function as intended can increase the risk of injury during a crash.
- Remedy
- Dealers will inspect and replace as necessary, the side impact crash sensors, free of charge. Owner notification letters were mailed on September 3, 2021. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2021070032/33.
Seat Belt Locking Retractor Malfunction/FMVSS 208
- Summary
- Mercedes-Benz, LLC (MBUSA) is recalling certain 2021 G550, AMG G63, E350, E450, AMG CLS53, AMG E53, AMG GT43, AMG GT53, AMG GT63, 2021-2022 CLS450, and AMG E63 vehicles. The rear seat belt automatic locking retractors may deactivate early, which can prevent the child restraint system from securing properly. As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard number 208, "Occupant Crash Protection."
- Consequence
- An unsecured child restraint system can increase the risk of injury during a crash.
- Remedy
- Dealers will inspect, and replace as necessary, the rear seat belt assemblies, free of charge. Owners notified of the voluntary recall campaign by an interim letter on August 13, 2021. A final letter was mailed on September 24, 2021. Owners may contact MBUSA customer service at 1-800-367-6372.
Rearview Camera Image May Not Display/FMVSS 111
- Summary
- Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2019-2021 CLA-Class, GLE/GLS-Class, A-Class, E-Class, E-Class Coupe and Convertible, GLA/GLB-Class, GLC-Class, CLS-Class, and AMG GT-Class 4-door Coupe vehicles. Please refer to MBUSA's recall report for specific vehicle model details. The MBUX multimedia system software may cause the display to remain black, or reboot after startup. This could result in the rearview camera image not displaying properly. As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard (FMVSS) number 111, "Rear Visibility."
- Consequence
- A backup camera that displays a blank image reduces the driver's rear view, increasing the risk of a crash or injury.
- Remedy
- The multimedia system software will be updated by a dealer, or through an over-the-air (OTA) update, free of charge. Owner notification letters were mailed beginning June 28, 2021. Owners may contact MBUSA customer service at 1-800-367-6373. MBUSA's number for this recall is 2021050012.
Rearview Camera and Parking Sensors Malfunction
- Summary
- Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 E350, E450, E450 Wagon, and AMG E63 vehicles. The parking control unit may fail to display the rearview camera image and cause the parking sensors to misidentify or fail to detect objects.
- Consequence
- An inoperative rearview camera display and/or parking sensors can reduce the driver's view and awareness of what is behind the vehicle, increasing the risk of a crash.
- Remedy
- All affected vehicles are still within MBUSA's control. MBUSA will replace the parking control unit, free of charge. The recall began April 8, 2021. Owner may contact MBUSA customer service at 1-800-367-6372.
Faulty Front Seat Position Switch
- Summary
- Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 C-Class, E-Class, E-Class Coupe and Convertible, GLC, CLS, AMG GT 4-door Coupe and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle model details. A faulty electrical contact within the seat position switch may prevent the driver and passenger air bags and seat belt force limiters from properly activating during a crash.
- Consequence
- Air bags and seat belts that do not perform properly in a crash can increase the risk of injury.
- Remedy
- MBUSA will notify owners, and dealers will replace the seat position switches, free of charge. Owner letters were mailed May 21, 2021. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2021040016.
Seat Limiter may Allow Seat too Close to Air Bag
- Summary
- Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 E350, E450, E450 Wagon, E63S AMG, 2020 E63S AMG Wagon, and 2020-2021 E53 AMG vehicles. The passenger seat limiter may allow the seat to be positioned too close to the air bag.
- Consequence
- A seat too close to the air bag increases the risk of injury in the event of a crash necessitating the deployment of the frontal passenger air bag.
- Remedy
- MBUSA will notify owners, and dealers will recalibrate the passenger seat limiter, free of charge. The recall began April 29, 2021. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2021040002.
Inaccurate Vehicle Location for Emergency Services
- Summary
- Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2016 - 2021 CLA-Class, GLA-Class, GLE-Class, GLS-Class, SLC-Class, A-Class, GT-Class, C-Class, E-Class, S-Class, CLS-Class, SL-Class, B-Class, GLB-Class, GLC-Class, and G-Class vehicles. Please refer to the Part 573 report for specific vehicle model details. The software design of the communication module may fail to communicate the correct vehicle location for the emergency call system (eCall) in the event of a crash.
- Consequence
- Failure of the eCall system may result in emergency responders being dispatched to the wrong location, increasing the risk of injury following a crash.
- Remedy
- MBUSA will notify owners, and the communication module software will be updated by a dealer, or through an over-the-air (OTA) update, free of charge. The recall began March 12, 2021. Owners may contact MBUSA customer service at 1-877-762-8267. MBUSA's number for this recall is 2021020025.
Front Passenger Seat Missing Adjustment Limit Stop
- Summary
- Mercedes-Benz USA, LLC. (MBUSA) is recalling certain 2021 E350 and E450, 2019-2021 AMG E53 and 2020-2021 AMG E63 vehicles. The front passenger seat may be missing the mechanical seat adjustment range limit stop, allowing the seat to move outside of the acceptable range in relation to the air bag.
- Consequence
- If the front passenger seat is adjusted beyond the acceptable range in relation to the air bag, there could be an increased risk of injury in the event of a crash with air bag deployment.
- Remedy
- MBUSA will notify owners, and dealers will inspect for the mechanical seat adjustment range limitation for the front passenger seat and install it if necessary, free of charge. The recall began December 18, 2020. Owners may contact MBUSA customer service at 1-800-368-6372. MBUSA's number for this recall is 2020110013.
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Owner complaints (13)
13 complaints filed with NHTSA (owner reports, not verified findings). The electrical system is mentioned most often.
As reported by owners in their complaints. These are reports, not NHTSA findings.
Most-reported components
| Component | Complaints | % of 13 |
|---|---|---|
| Electrical system | 4 | 30.8% |
| Engine | 4 | 30.8% |
| Back over prevention | 3 | 23.1% |
| Power train | 3 | 23.1% |
| Fuel/propulsion system | 2 | 15.4% |
| Fuel system | 1 | 7.7% |
| Service brakes | 1 | 7.7% |
How 2021 compares with other E350 years
Best and worst E350 years →| Model year | Complaints | Recall campaigns |
|---|---|---|
| 2015 | 31 | 6 |
| 2016 | 51 | 5 |
| 2017 | 7 | 0 |
| 2020 | 8 | 6 |
| 2021 | 13 | 12 |
| 2022 | 8 | 3 |
| 2023 | 6 | 3 |
| 2024 | 5 | 4 |
| 2025 | 2 | 2 |
| 2026 | 1 | 1 |
Counts are owner reports, not failure rates. Higher sales years tend to draw more reports. Owners are still filing reports for recent model years, so these counts will grow. Source: NHTSA ODI, retrieved Oct 6, 2026.
Fuel economy: up to 25 mpg combined
- EPA annual fuel cost
- $3,300
- CO₂ tailpipe
- 349 g/mi
- EPA class
- Midsize Cars
What it costs you to run
Miles ÷ 25 mpg × $4.354 (EIA US average regular, week of Oct 5, 2026, all taxes included). Source: EPA · EIA.
EPA label estimates from lab tests; your mileage will vary.
Specs by configuration
| Engine · transmission | Drive | City / Hwy / Comb | EPA $/yr | CO₂ g/mi |
|---|---|---|---|---|
| 2 L 4-cyl · 9-speed automatic | Rear-Wheel Drive | 22 / 31 / 25 | $3,300 | 349 |
Source: EPA fuel economy data, retrieved Oct 6, 2026. Configurations are listed when EPA and NHTSA records match.

Looking at a 2021 E350 for sale?
Print a one-page buyer's checklist: each recall campaign with a box to tick when the seller shows proof of repair, the top complaint areas to inspect, crash stars, MPG, and a link back to this page.
Where to next
2021 Mercedes-Benz E350 FAQ
How many recalls does the 2021 Mercedes-Benz E350 have?
NHTSA lists 12 recall campaigns: 23V445000 (fuel pump), 22V365000 (electrical), 22V232000 (rear camera), 22V189000 (steering), 21V527000 (air bag), 21V483000 (seat belt), 21V354000 (electrical), 21V228000 (rear camera), 21V230000 (air bag), 21V216000 (seat), 21V058000 (electrical), 20V673000 (seat). Use NHTSA's VIN lookup to see whether a specific car was repaired.
What are the most common 2021 Mercedes-Benz E350 problems?
Owners filed 13 complaints with NHTSA. Electrical system (4), Engine (4), Back over prevention (3) are mentioned most. These are owner reports, not verified findings.
What mpg does the 2021 Mercedes-Benz E350 get?
EPA rates the 2 L 4-cyl · 9-speed automatic version at 22 city, 31 highway and 25 combined mpg.
How does the 2021 E350 compare with other years?
Among the 2015–2021 Mercedes-Benz E350 model years at least five years old, the 2017 drew the fewest complaints (7) and the 2016 the most (51). The 2021 drew 13. Counts are owner reports, not failure rates.
How this page was madeSources, processing, limits, review and changes
Data sources
- NHTSA recalls by vehicle
Retrieved Oct 6, 2026 - US DOT recall completion rates (data.transportation.gov)
Retrieved Oct 6, 2026 - NHTSA ODI owner complaints
Retrieved Oct 6, 2026 - NHTSA NCAP 5-Star Safety Ratings
Retrieved Oct 6, 2026 - EPA fuel economy data (licence confirmation pending)
Retrieved Oct 6, 2026 - EIA weekly retail gasoline prices
Weekly, all taxes included
Processing
- Complaints are counted per component. One complaint can list several, so component totals add up to more than the total.
- Fuel cost = miles per year ÷ EPA combined mpg × EIA weekly price for your region.
Limitations
- Complaint counts are owner reports, not verified findings or failure rates. There is no sales denominator.
- Recall campaigns are listed for the model year. Only NHTSA and the automaker know whether a specific car was repaired.
- Recent model years are still collecting reports.
Review
Data compiled automatically from the official files listed here.
Changelog
- 2026-10-06 Data refreshed from the official files.