Independent · Not affiliated with NHTSA or any automaker MethodologyData sourcesData refreshed Oct 6, 2026

2022 Mercedes-Benz E 450: Problems, Recalls and MPG

What this means

NHTSA lists 5 recall campaigns for the 2022 Mercedes-Benz E 450, most recently filed February 2024. Owners have filed 11 complaints with NHTSA, most often about the electrical system.

Data summary generated from official records. Methodology Data: NHTSA, DOT, EPA · Refreshed Oct 6, 2026
Caution Fewer than 50 complaints filed. With this few reports, patterns may not be meaningful.
Compare

Recalls (5)

NHTSA lists 5 recall campaigns for the 2022 Mercedes-Benz E 450. Check whether yours was repaired with NHTSA's free VIN lookup ↗

Only NHTSA and your automaker know whether your specific car was repaired. PlainVIN shows every recall campaign listed for a model year, with the official text and how many cars have been fixed so far.

Check on NHTSA ↗
Listed for 2022 Mercedes-Benz E 450. Not checked against your VIN.
Recall 24V100000 Filed Feb 9, 2024

48-Volt Ground Cable Not Tightened Properly

Electrical system · wiring
Official NHTSA text
Summary
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 CLS450, E450, E450 All-Terrain, AMG E53, AMG GT43, AMG GT53, and 2021 AMG CLS53 vehicles. The 48-volt ground cable connection located in the engine compartment may not be tightened properly and may result in the ground cable overheating.
Consequence
An overheated ground cable increases the risk of a fire.
Remedy
Dealers will inspect the 48-volt ground cable connection and repair it as necessary, free of charge. Owner notification letters were mailed March 22, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2024MMNNNN.
95.3% repairedof 12,191 vehicles
Manufacturer report to NHTSA · Source: US DOT recall completion data, retrieved Oct 6, 2026
Check your VIN on NHTSA or ask a dealer to check campaign 24V100000
Listed for 2022 Mercedes-Benz E 450. Not checked against your VIN.
Recall 23V880000 Filed Dec 21, 2023

Fuel Pump Shutdown May Cause Loss of Drive Power

Fuel system, gasoline · delivery · fuel pump
Official NHTSA text
Summary
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2024 GLE, GLS, C-Class, E-Class, S-Class, SL, GLC, CLS, AMG GT, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, causing a loss of drive power.
Consequence
A loss of drive power can increase the risk of a crash.
Remedy
Dealers will replace the fuel pump, free of charge. Owner notification letters were mailed on June 28, 2024. Owner notification letters will be mailed in phases, on February 23, 2024, April 19, 2024, June 28, 2024, August 9, 2024, October 1, 2024, and December 2, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. This recall is an expansion of NHTSA recall number 23V-445.
88.6% repairedof 79,676 vehicles
Manufacturer report to NHTSA · Source: US DOT recall completion data, retrieved Oct 6, 2026
Check your VIN on NHTSA or ask a dealer to check campaign 23V880000
Listed for 2022 Mercedes-Benz E 450. Not checked against your VIN.
Recall 23V445000 Filed Jun 26, 2023

Loss of Drive Power from Fuel Pump Shutdown

Fuel system, gasoline · delivery · fuel pump
Official NHTSA text
Summary
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 C-Class, E-Class, S-Class, CLS, SL, GT, GLC, GLE, GLS, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, which can result in a loss of drive power.
Consequence
A loss of drive power can increase the risk of a crash.
Remedy
Dealers will replace the fuel pump, free of charge. Owner notification letters were mailed on June 14, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2023070012.
92.2% repairedof 143,551 vehicles
Manufacturer report to NHTSA · Source: US DOT recall completion data, retrieved Oct 6, 2026
Check your VIN on NHTSA or ask a dealer to check campaign 23V445000
Listed for 2022 Mercedes-Benz E 450. Not checked against your VIN.
Recall 22V733000 Filed Sep 30, 2022

Disabled Safety Features from Unsecure 12V Battery

Electrical system · 12v/24v/48v battery
Official NHTSA text
Summary
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2019-2022 CLS450 Coupe and AMG E53, 2019-2021 AMG CLS53 Coupe, and 2021-2022 E450 vehicles. The 12-Volt battery in the trunk may not be properly secured, which, in the event of a crash, can cause electrical connection failure, disabling various safety features including, emergency call (eCall) system, electric seat adjustment, hazard warning lights, and automatic door locks.
Consequence
The inability to operate safety features (eCall system, hazard lights, electric seats, or automatic door locks) can increase the risk of injury during a crash.
Remedy
Dealers will secure the 12V battery, free of charge. Owner notification letters were mailed January 20, 2023. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022100009.
92.8% repairedof 19,968 vehicles
Manufacturer report to NHTSA · Source: US DOT recall completion data, retrieved Oct 6, 2026
Check your VIN on NHTSA or ask a dealer to check campaign 22V733000
Listed for 2022 Mercedes-Benz E 450. Not checked against your VIN.
Recall 22V189000 Filed Mar 25, 2022

Steering Wheel Hands-Off Detection Software Error

Steering · steering wheel/handle bar
Official NHTSA text
Summary
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2022 C-Class, E-Class, S-Class, SL, EClass Coupe/Convertible, CLS, AMG GT 4-doors Coupe, and EQS vehicles with a heated leather steering wheel. Due to a software error in the hand detection control unit, the hands-off detection might not detect when the driver's hands are away from the steering wheel when using the Active Distance Assist DISTRONIC system.
Consequence
Deactivated hands-off detection will prevent DISTRONIC system features from functioning, including warnings to grab the steering wheel and calling first responders as part of the Active Emergency Stop Assist, which can increase the risk of a crash or injury.
Remedy
Dealers will update the hand detection control unit software for the DISTRONIC system, free of charge. Owner notification letters were mailed May 6, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022040010.
97.9% repairedof 8,396 vehicles
Manufacturer report to NHTSA · Source: US DOT recall completion data, retrieved Oct 6, 2026
Check your VIN on NHTSA or ask a dealer to check campaign 22V189000

PlainVIN shows public government records for education. It isn't a vehicle inspection or legal advice. Check your own VIN with NHTSA or your dealer.

Owner complaints (11)

11 complaints filed with NHTSA (owner reports, not verified findings). The electrical system is mentioned most often.

0involved a crash
0involved a fire
0injuries reported
0deaths reported

As reported by owners in their complaints. These are reports, not NHTSA findings.

Most-reported components

Complaints filed with NHTSA for the 2022 Mercedes-Benz E 450, by component (top 10). One complaint can list several components, so these add up to more than 11.Source: NHTSA ODI owner complaints · Retrieved Oct 6, 2026 · Report a data error

How 2022 compares with other E 450 years

Best and worst E 450 years →
17 9 7 11 17 2
201920202021202220232024
This year (2022)Other yearsStill collecting reports

Counts are owner reports, not failure rates. Higher sales years tend to draw more reports. Owners are still filing reports for recent model years, so these counts will grow. Source: NHTSA ODI, retrieved Oct 6, 2026.

Fuel economy: up to 25 mpg combined

25
mpg combined
22
city
29
highway
EPA annual fuel cost
$3,300
CO₂ tailpipe
360 g/mi
EPA class
Subcompact Cars

What it costs you to run

$2,612per year
$218per month
600gallons a year

Miles ÷ 25 mpg × $4.354 (EIA US average regular, week of Oct 5, 2026, all taxes included). Source: EPA · EIA.

EPA label estimates from lab tests; your mileage will vary.

Specs by configuration

2022 Mercedes-Benz E 450 configurations with EPA data
Engine · transmissionDriveCity / Hwy / CombEPA $/yrCO₂ g/mi
3 L 6-cyl · 9-speed automaticRear-Wheel Drive22 / 29 / 25$3,300360
3 L 6-cyl · 9-speed automaticRear-Wheel Drive22 / 29 / 25$3,300360

Source: EPA fuel economy data, retrieved Oct 6, 2026. Configurations are listed when EPA and NHTSA records match.

Used blue SUV on a sunny dealer lot with its hood open and a clipboard on the fender

Looking at a 2022 E 450 for sale?

Print a one-page buyer's checklist: each recall campaign with a box to tick when the seller shows proof of repair, the top complaint areas to inspect, crash stars, MPG, and a link back to this page.

All E 450 years

Where to next

2022 Mercedes-Benz E 450 FAQ

How many recalls does the 2022 Mercedes-Benz E 450 have?

NHTSA lists 5 recall campaigns: 24V100000 (electrical), 23V880000 (fuel pump), 23V445000 (fuel pump), 22V733000 (electrical), 22V189000 (steering). Use NHTSA's VIN lookup to see whether a specific car was repaired.

What are the most common 2022 Mercedes-Benz E 450 problems?

Owners filed 11 complaints with NHTSA. Electrical system (4), Fuel system (2), Service brakes (2) are mentioned most. These are owner reports, not verified findings.

What mpg does the 2022 Mercedes-Benz E 450 get?

EPA rates the 3 L 6-cyl · 9-speed automatic version at 22 city, 29 highway and 25 combined mpg. Other configurations are listed in the fuel economy section.

How does the 2022 E 450 compare with other years?

Among the 2019–2021 Mercedes-Benz E 450 model years at least five years old, the 2021 drew the fewest complaints (7) and the 2019 the most (17). The 2022 drew 11. Counts are owner reports, not failure rates.

How this page was madeSources, processing, limits, review and changes

Processing

  • Complaints are counted per component. One complaint can list several, so component totals add up to more than the total.
  • Fuel cost = miles per year ÷ EPA combined mpg × EIA weekly price for your region.

Limitations

  • Complaint counts are owner reports, not verified findings or failure rates. There is no sales denominator.
  • Recall campaigns are listed for the model year. Only NHTSA and the automaker know whether a specific car was repaired.
  • Recent model years are still collecting reports.

Review

Data compiled automatically from the official files listed here.

Changelog

  • 2026-10-06 Data refreshed from the official files.
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