Independent · Not affiliated with NHTSA or any automaker MethodologyData sourcesData refreshed Oct 6, 2026

2021 Mercedes-Benz S500: Problems, Recalls and MPG

What this means

NHTSA lists 7 recall campaigns for the 2021 Mercedes-Benz S500, most recently filed February 2025. Owners have filed 1 complaints with NHTSA, most often about the engine and engine cooling.

Data summary generated from official records. Methodology Data: NHTSA, DOT, EPA · Refreshed Oct 6, 2026
Caution Fewer than 50 complaints filed. With this few reports, patterns may not be meaningful.
Compare

Recalls (7)

NHTSA lists 7 recall campaigns for the 2021 Mercedes-Benz S500. Check whether yours was repaired with NHTSA's free VIN lookup ↗

Only NHTSA and your automaker know whether your specific car was repaired. PlainVIN shows every recall campaign listed for a model year, with the official text and how many cars have been fixed so far.

Check on NHTSA ↗
Listed for 2021 Mercedes-Benz S500. Not checked against your VIN.
Recall 25V116000 Filed Feb 24, 2025

Front Brake Hose May Leak

Service brakes, hydraulic · foundation components
Official NHTSA text
Summary
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2022 S 500, Maybach S 580 4MATIC, 2021-2023 S 580 4MATIC, 2022 S 680 4MATIC, and 2023 S 580e 4MATIC vehicles. The front brake hoses may rupture and leak brake fluid.
Consequence
A brake fluid leak can extend the distance needed to stop the vehicle, increasing the risk of a crash.
Remedy
Dealers will replace the front brake hoses, free of charge. Owner notification letters were mailed April 25, 2025. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2025030007.
80.4% repairedof 20,339 vehicles
Manufacturer report to NHTSA · Source: US DOT recall completion data, retrieved Oct 6, 2026
Check your VIN on NHTSA or ask a dealer to check campaign 25V116000
Listed for 2021 Mercedes-Benz S500. Not checked against your VIN.
Recall 24V807000 Filed Oct 25, 2024

Disabled Emergency Call System

Communication · auto crash notification
Official NHTSA text
Summary
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 Maybach S 580 4MATIC, S 500 4MATIC, and S 580 4MATIC vehicles. The emergency call system may fail to place an automatic or manual call and may not provide the vehicle location as intended.
Consequence
A disabled emergency call system that prevents a vehicle occupant from contacting emergency services or fails to identify the vehicle location, can delay emergency responders and increase the risk of injury.
Remedy
Dealers will update the communication module software, free of charge. Owner notification letters were mailed December 6, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2024110002.
57.1% repairedof 21 vehicles
Manufacturer report to NHTSA · Source: US DOT recall completion data, retrieved Oct 6, 2026
Check your VIN on NHTSA or ask a dealer to check campaign 24V807000
Listed for 2021 Mercedes-Benz S500. Not checked against your VIN.
Recall 22V493000 Filed Jul 11, 2022

Inoperative Rearview Camera Display/FMVSS 111

Back over prevention · display function
Official NHTSA text
Summary
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2022 AMG EQS53, EQS580, EQS450, 2021 S500, S580, and Maybach S580 vehicles. The rearview camera may not display the rearview image due to a software error in the MBUX multimedia system. As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard number 111, "Rear Visibility."
Consequence
An inoperative rearview camera display reduces the driver's rear view, increasing the risk of a crash.
Remedy
Dealers will update the MBUX multimedia system software, free of charge. Owner notification letters are expected to be mailed August 19, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022080002.
96.1% repairedof 8,530 vehicles
Manufacturer report to NHTSA · Source: US DOT recall completion data, retrieved Oct 6, 2026
Check your VIN on NHTSA or ask a dealer to check campaign 22V493000
Listed for 2021 Mercedes-Benz S500. Not checked against your VIN.
Recall 22V365000 Filed May 20, 2022

Disabled Emergency Call System

Communication · auto crash notification
Official NHTSA text
Summary
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2017-2022 CLA-Class, GLA-Class, GLE-Class, GLS-Class, SLC-Class, A-Class, AMG GT-Class, C-Class, E-Class, S-Class, SL-Class, GLC-Class, CLS-Class, GLB-Class, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle model details. An error in the communication module's SIM card software can cause a mobile network connection failure, disabling the emergency call (eCall) system.
Consequence
A disabled eCall system would prevent a vehicle occupant from contacting the emergency services call center in an emergency, potentially delaying emergency responders and increasing the risk of injury.
Remedy
The communication module software will be updated through an Over-the-Air (OTA) update or by a dealer, free of charge. Owner notification letters were mailed July 8, 2022. Owner notification letters will be mailed in phases, on July 8, 2022, May 17, 2024, July 29, 2024, and September 27, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's numbers are for this recall is 2022060005 and 2023110006.
90.6% repairedof 242,722 vehicles
Manufacturer report to NHTSA · Source: US DOT recall completion data, retrieved Oct 6, 2026
Check your VIN on NHTSA or ask a dealer to check campaign 22V365000
Listed for 2021 Mercedes-Benz S500. Not checked against your VIN.
Recall 22V214000 Filed Apr 1, 2022

Unsecured Steering Module Electrical Connector

Steering · column
Official NHTSA text
Summary
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 S580 4Matic and S500 4Matic vehicles. The electrical connector to the steering column module may not be secured properly, which can disable gear shifts and/or safety features including the electronic stability program, the driver's air bag, and turn signal indicators.
Consequence
Disabled safety features or the inability to shift gears can increase the risk of a crash or injury.
Remedy
Dealers will inspect and reinstall the cover for the electrical connector, as necessary, free of charge. Owner notification letters were mailed May 13, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022040006.
100% repairedof 4 vehicles
Manufacturer report to NHTSA · Source: US DOT recall completion data, retrieved Oct 6, 2026
Check your VIN on NHTSA or ask a dealer to check campaign 22V214000
Listed for 2021 Mercedes-Benz S500. Not checked against your VIN.
Recall 22V167000 Filed Mar 18, 2022

Disabled Rear Lighting

Exterior lighting · back up lights
Official NHTSA text
Summary
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2022 EQS 450, EQS 580, and 2021 S500 and S580 vehicles. A software error may disable the rear turn signals, hazard lights, and reverse lights.
Consequence
Disabled rear turn signals, hazard lights, and reverse lights can reduce the vehicle's visibility to other driver's, increasing the risk of a crash.
Remedy
Dealers will update the rear signal software, free of charge. Owner notification letters were mailed May 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022040013.
97.4% repairedof 9,156 vehicles
Manufacturer report to NHTSA · Source: US DOT recall completion data, retrieved Oct 6, 2026
Check your VIN on NHTSA or ask a dealer to check campaign 22V167000
Listed for 2021 Mercedes-Benz S500. Not checked against your VIN.
Recall 21V789000 Filed Oct 11, 2021

Deactivated Front Passenger Air Bag

Air bags · air bag/restraint control module · software
Official NHTSA text
Summary
Mercedes-Benz USA, LLC. (MBUSA) is recalling certain 2021 S500, S580, and Maybach S580 vehicles. The air bag control unit software may deactivate the occupant recognition control unit, resulting in a deactivated front passenger air bag.
Consequence
A deactivated passenger air bag increases the risk of injury during a crash.
Remedy
Dealers will update the air bag control unit software, free of charge. Owner notification letters were mailed December 1, 2021. MBUSA's number for this recall is 2021100010. Owners may contact MBUSA customer service at 1-800-367-6372.
98.2% repairedof 1,311 vehicles
Manufacturer report to NHTSA · Source: US DOT recall completion data, retrieved Oct 6, 2026
Check your VIN on NHTSA or ask a dealer to check campaign 21V789000

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Owner complaints (1)

1 complaints filed with NHTSA (owner reports, not verified findings). The engine and engine cooling is mentioned most often.

0involved a crash
0involved a fire
0injuries reported
0deaths reported

As reported by owners in their complaints. These are reports, not NHTSA findings.

Most-reported components

Complaints filed with NHTSA for the 2021 Mercedes-Benz S500, by component (top 1). One complaint can list several components, so these add up to more than 1.Source: NHTSA ODI owner complaints · Retrieved Oct 6, 2026 · Report a data error

How 2021 compares with other S500 years

Best and worst S500 years →
2001200220032004200520062007202120222023
This year (2021)Other yearsStill collecting reports

Counts are owner reports, not failure rates. Higher sales years tend to draw more reports. Owners are still filing reports for recent model years, so these counts will grow. Source: NHTSA ODI, retrieved Oct 6, 2026.

Used blue SUV on a sunny dealer lot with its hood open and a clipboard on the fender

Looking at a 2021 S500 for sale?

Print a one-page buyer's checklist: each recall campaign with a box to tick when the seller shows proof of repair, the top complaint areas to inspect, crash stars, MPG, and a link back to this page.

All S500 years

Where to next

2021 Mercedes-Benz S500 FAQ

How many recalls does the 2021 Mercedes-Benz S500 have?

NHTSA lists 7 recall campaigns: 25V116000 (brake), 24V807000 (electrical), 22V493000 (rear camera), 22V365000 (electrical), 22V214000 (steering), 22V167000 (lighting), 21V789000 (air bag). Use NHTSA's VIN lookup to see whether a specific car was repaired.

What are the most common 2021 Mercedes-Benz S500 problems?

Owners filed 1 complaints with NHTSA. Engine and engine cooling (1) are mentioned most. These are owner reports, not verified findings.

How does the 2021 S500 compare with other years?

Among the 2001–2021 Mercedes-Benz S500 model years at least five years old, the 2021 drew the fewest complaints (1) and the 2001 the most (34). The 2021 drew 1. Counts are owner reports, not failure rates.

How this page was madeSources, processing, limits, review and changes

Processing

  • Complaints are counted per component. One complaint can list several, so component totals add up to more than the total.
  • Fuel cost = miles per year ÷ EPA combined mpg × EIA weekly price for your region.

Limitations

  • Complaint counts are owner reports, not verified findings or failure rates. There is no sales denominator.
  • Recall campaigns are listed for the model year. Only NHTSA and the automaker know whether a specific car was repaired.
  • Recent model years are still collecting reports.

Review

Data compiled automatically from the official files listed here.

Changelog

  • 2026-10-06 Data refreshed from the official files.
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